I run the latest version of Norton 360 on my MC Server and MC Client.
Apart from a couple of minor issues when 360 has been upgraded and incorporated new technology that found new issues, which I then had to tell it were okay, I haven't had any problem. The issues were things like I had to tell the firewall MC21 was okay after upgrading from MC20, I think the WDM Driver needed some attention, and when I installed the Windows 10 compatible version of 360, which was a major upgrade. I am still on Windows 7 though as well. I just don't turn on silent mode, so I see the prompts from 360 to do something about what it thinks are firewall incursions, virus, or malware activities.
Basically, I can and do recommend Norton 360 as one of the better security suites these days. It works fine with MC.
The Five Device licence is a better deal than the individual licences as well, if you haven't upgraded to that yet. I can install it on Windows, Macs, some phones, etc., all on the one licence.