This is all I know. I think you have to import the file, not open it.
Here is how it works:
1. Make a folder on your computer.
2. Set MC to auto import Playlist > TitanTV Program Info (tvpi, tvvi) from the folder.
3. You must already have respective TV channels setup in MC.
4. Go to TitanTV web site. Setup your own TV lineup and display it.
5. Choose a program by click the guide cell. If it is a currently airing program, a "Play" icon will be displayed, along with a "Record" icon and some other icons, in a pop-up. If the program is a future program, the "Play" icon will be missing.
6. Click either "Play" or "Record" icon. You will be prompted to save a file on your computer. The default file name is "Program.tvpi" for recording, or "Program.tvvi" for viewing live. Save the file in the folder you created in step 1 and had MC watching in step 2.
7. Once the file is saved, MC will pick it up and use the info in the file to either run TV tuner for viewing, or schedule to record the program. Once MC finishes using the file, it will delete it.