Does it go away if you uncheck Memory Playback?
There are some other threads right now that make me suspicious that this feature might be broken in certain conditions. I don't know specifics, but look around at some of the other recent threads on the Mac board. Also, try searching the forum for the name of your DAC. I remember (vaguely) seeing stuff about those DACs. There might be driver weirdness or something.
If unchecking Memory Playback "fixes" it, please report back. They're working on this currently, I believe.
If not, I'd investigate the drivers for your DAC, as the problem (assuming there isn't some weird bug with that DAC and the current builds of MC) probably lies in there, and maybe it is fixed in a newer (or older) driver version.
Lastly, blindly unchecking everything in the General > Features Options section isn't generally a good idea. To be clear, this does NOT reduce the "footprint" of MC in any discernible way (it still "loads" the code for all that stuff, or the vast majority of it). That just hides and/or disables that functionality.
It is a good way to get rid of something that irritates you because you accidentally bumble into it and you don't need it. It is not a "I don't need this and it'll run better if I have it as clean as is possible" thing.
For example, I'm not sure at all what happens if you uncheck Data Support and Linkable Columns. Might that cause weirdness? Maybe? That's almost certainly NOT the problem here, I just wanted to point out that this is generally a bad idea. This section of MC's Options is considered "Advanced" and unsupported. In there be dragons.
As I said, that's almost certainly not the problem here. But I just wanted to mention that... Well...
I don't think that means what you think it means.