Just FYI, I'm now using Windows 10 (build 10166) as my everyday Windows VM on my Macbook Pro. I've been using MC on it some there, and it has no issues at all with the current builds.
I've also been running Windows 10 in VMs for test purposes, and testing MC, since the first public "Insider" release. Other than the times when Windows 10 was hosed, such as when it couldn't run any win32 apps at all or the most recent bad build that only lasted a day, I've had zero issues with MC the whole time.
It runs just as it does with Windows 8.1, and there are even nice new toolbar close/min/max icons that match the UI style.