Windows Sound has nothing to do in this situation, I am using DLNA with an external renderer, the sound is streamed through network.
I am not an expert but as far as I know in this arrangement the signal is not processed inside the PC, but inside external renderer, there is no Windows driver to alter the signal between the file and the speaker. Actually this is what I really like about DLNA, your quality is only affected by the quality of the audio components you use , not by some Windows driver that was crippled by a Microsoft update.
You are mentioning ASIO or WASAPI, you probably are already listening to a degraded version of the sound, altered by these drivers, so there is no difference for you. I may be wrong, but that's how I understand that the things work.
I am not using any DSP Studio feature and the output is set to PCM 24bit 96 kHz, same as the bitrate and depth of the song, but I tried also with "Same as source" setting in both MC21 and MC22. Same renderer, same settings, same network, same song.