Is it possible to make such a skin?
Or perhaps just a track info template?
No, it's not possible...
Transparency from PNG files is only possible in front of MC's background, not in front of the desktop or other programs. Therefore it can only be used for buttons, icons, sliders (in MEGA-ME) and maybe some other parts in mini-me.
Transparency from a defined transparency color for PNG, GIF or BMP files can be used even in front of the desktop or other programs (only 100% transparency...). This is how the rounded border edges of some skins are made, for example. One could make a mini-me skin with a "hole" where you can look through, but I don't know if this would be more than just a joke... It doesn't make much sense for MEGA-ME.
You can not use transparency for lists or TrackInfo backgrounds... if you are missing your messenger late at night, try the windows taskbar
BTW... Was your bios field problem solved?