I'm even more interested in this now. I just installed Windows 7 on my Macbook Pro, and am using it for my one-and-only copy of iTunes. In setting that up, I switched over to AVG Internet Security (I use an old Corporate Symantec AV on my WinXP installs, from before they made it all bloated and terrible). Unfortunately, I discovered today that AVG's resident protection blocks iTLU, which I'm currently using to sync my iTunes library to the "handheld" folder on my hard drive (which MC syncs to).
So now, to sync my phone, it is a huge multi-step process made one step harder by the need to manually go in and disable AVG (a process which takes like 6 clicks and a UAC prompt). Either that, or I need to find a different A/V application (equally annoying).
So here's hoping that this'll end up working, and secondarily that it'll work with anti-virus protection turned on!