I also upgraded to iTUnes v10. I tried to quickly verify that I had no sync issue like the one TXgary reported (134 files that always sync). I found an issue and did many tests to try to duplicate the pattern.
Basic findings:
1) I sync everything
2) I sync again - expect nothing will sync (as everything was in sync with step 1)
3) I find tracks that sync again.
4) I delete all tracks that are being sync'd from both the MC library and iTunes library
5) I sync again, and 0 tracks are sync'd (as expected)
6) In MC I select a track and start to play it. I cancel the play.
7) I sync - 1 file is sync'd (as expected)
I sync again - the same file is sync'd again even though I did not play it again.
9) Any additional files I play add to the pattern - e.g. if play 10 files, all 10 will always sync
So something is different in either iTunes 10 or a very new MC release. The files that were showing up that caused me to test further in my 1st test were ripped and imported on September 1. I think I had already upgraded to iTunes 10. Following is an example from my log file.
<MC Version="15.0.105" LibraryName="Default" LibraryPath="C:\Users\Home\AppData\Roaming\J River\Media Center 15\Library\" />
<iTunes Version="10.0.0.68" />
- <Track Filename="M:\My Music Collection\Janis Joplin\Pearl\Janis Joplin - Cry Baby (Live).mp3">
<LastSkipped ChangedIn="iTunes" OldValue="2010-09-02T14:18:49" NewValue="2010-09-02T21:18:49" />
EDIT: note that the cool face is not by design - it is parenthesis 8