Have you heard about this. Flirc ? A friend uses this and its cross platform, he seems to think its great - he uses his fancy high end audio looking remote for everything. http://flirc.tv/product/flirc/
I have, but it doesn't really work for me. I'm looking for a single remote which can control my TV, DAC, and Media Center.
If I did not currently have a Sony TV, I would probably buy something like that along with
this Sony remote, and use it to control Media Center.
The remote likely shares at least some IR codes with my current TV though, so it would not be possible to use with Media Center. (because button presses will be sent to both the TV and PC at the same time)
From my gaming days take with a grain of salt ... certain gaming mice have interfaces that allow you to do all sorts of things and with different profiles -- most of the time I used this for loading addons, changes to sensitivity on the fly, etc. But, if you have the mouse drivers installed, you can use this to load different devices, controllers etc with mapped hot keys for each. Probably would work with a remote if seen as a device but is complicated (and the mouse would have to be connected to a USB port. Unless you are a hard core player with 80 euro+ gaming mice already, and then you know what I'm talking about, I'd leave this suggestion alone^^).
My current solution is actually to use
Xpadder and a wireless Xbox 360 controller as a remote.
It works reasonably well, but the problem is that it's completely unintuitive for anyone else to use, and powers off after 15 minutes of being idle.
If I'm in front of the PC, I just use the regular mouse interface.
I've tried apps like JRemote, but I really don't like touchscreen controls, or having to unlock a device, load an app, wait for it to connect, and
then be able to control the PC.