I'm going to add some diagnosis procedure here. These may help narrow the source of the problem.
Does the program disappear? That's a crash. If it just freezes, that's a hang. Let us know which it is. The thread is for crashes. A hang can happen if the OS doesn't allow interaction with MC because it's too busy.
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What version of MC are you using?
Have you configured
Windows Defender?
Are you using any other antivirus. If so, uninstall it, just to test.
Does it behave the same way on another machine?
Is the media on a local library? Or is it on a NAS or USB drive?
What type of files?
What OS? Is it up to date?
Are your drivers up to date?
Try turning off auto-import in the Tools menu.
What are you playing to? How is it connected? Test playback to another device. Switch among audio via ASIO, HDMI, and Direct Sound.